Cu-Catalyzed Asymmetric Hydroboration of Naphthylallylic Compounds for Enantioselective Synthesis of Chiral Boronates

A Cu-catalyzed regio- and enantioselective hydroboration of various naphthylallylic compounds affording chiral boronates with high yields and excellent enantioselectivities (up to 96% ee) was presented. The utility of the boronated products is further illustrated by other stereospecific C–B bond transformations to produce amino alcohols and other useful compounds.