lncRNA MALAT-1 Predicts Prognosis of Patients with Systemic Lupus Erythematosus

Objective To evaluate the association of MALAT-1 and the prognosis of patients with systemic lupus erythematosus (SLE). Materials and Methods A total of 87 SLE patients and 50 healthy controls were recruited. The expression levels of MALAT-1 were measured by quantitative PCR at baseline. Multivariate Cox regression analysis was performed to assess the association of MALAT-1 levels with survival after adjusting for potential confounding factors. Results The MALAT-1 levels in patients with SLE were significantly higher compared with healthy controls (p Conclusion The expression levels of MALAT-1 may be a promising biomarker for evaluating the prognosis of SLE patients.