Vibration disease in miners of the Far North

: The article covers a specified concept model of vibration disease pathogenesis. The leading mechanisms underlying the disease are nervous and hormonal dysfunction presenting hypercortisolemia and low serum levels of thyroid hormones, associated tunnel compression of upper limb nerves and immune disorders resulting in autoimmune aggression. Informative diagnostic methods are suggested and diagnostic values are justified. The authors proved efficiency of therapeutic measures aimed to relieve compression and ischemic changes in peripheral nerves, to correct immune disorders.