Phase I trial to investigate the effect of renal impairment on isavuconazole pharmacokinetics

Robert Townsend,Shahzad Akhtar,Harry Alcorn,Jolene Kay Berg,Donna Kowalski,Salim Mujais,Amit Desai

Phase I trial to investigate the effect of renal impairment on isavuconazole pharmacokinetics

2017

Robert Townsend
Shahzad Akhtar
Harry Alcorn
Jolene Kay Berg
Donna Kowalski
Salim Mujais
Amit Desai

Purpose The purpose of the study is to evaluate the effect of renal impairment (RI) and end-stage renal disease (ESRD) on the pharmacokinetics (PK) of isavuconazole and the inactive cleavage product, BAL8728.

Keywords:

Anesthesia
Medicine
Diabetes mellitus
Disease
Intensive care medicine
Pharmacokinetics
Pharmacology
end stage renal disease
pharmacology toxicology

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