A scaffold protein that chaperones a cysteine-sulfenic acid in H2O2 signaling

The H2O2-responsive transcription factor Yap1 undergoes oxidative activation mediated by the peroxidase Orp1. In vitro reconstitution of the redox relay revealed a role for the Yap1-binding protein Ybp1 in promoting the formation of a ternary complex with Orp1 and Yap1 to enable redox transfer.