Treatment of small non-cleaved cell lymphoma in the adult

Small non-cleaved cell lymphoma is one of the most rapidly growing malignancies and in children is highly curable. However, in adults, the disease is disseminated in approximately one half of the patients, and with standard chemotherapy used for lymphoma, is less curable than it is in children, especially in patients presenting with bone marrow involvement. However, recent developments in clinical management using intensive dose therapy for this disease have improved the eventual outcome for these patients. This review focuses on some of these improvements.