Various approaches to optimizing the hemodynamics of myocardial infarct patients

: Combined investigation of systemic and intracardiac hemodynamic parameters (radiocardiography and Fick's procedure, transvenous catheterization, and right-ventricular and pulmonary arterial blood pressure measurement) was carried out in 428 myocardial infarction patients admitted to hospital within the early hours after the attack; changes in necrotic area were monitored for 7 days (precordial ECG cartography and serial serum CPK assays). Computer-assisted combined data analysis made use of image identification techniques, the images being based on a general approximation algorithm and informative coefficient. The algorithm permitted a classification of patients' condition by left-ventricular insufficiency (a 77.4% reliability) and by the spread of necrotic area (a 72.5% reliability). The prognosis chart, constructed on the basis of comparison between actual hemodynamic values and their standard vectors, brought out optimum regimens for every parameter associated with the least risk of left-ventricular insufficiency and necrotic spread.