[The correlations between C-reactive protein to albumin ratio and postoperative complications in patients with colorectal surgery].
2020
Objective: To examine the correlations of C-reactive protein (CRP)/albumin ratio (CAR) with the postoperative complications of patients with colorectal cancer. Methods: The clinic data of 312 patients undergoing elective surgery for colorectal cancer in Hainan Hospital of People's Liberation Army General Hospital between January 2013 and July 2018 was analyzed retrospectively. There were 188 males and 124 females, aged (61.0±12.9) years (range: 21 to 86 years). Logistic analysis was used to identify relative factors for postoperative complications. Receiver operating characteristic curves were developed to examine the cutoff values and compared diagnostic accuracy of the CAR and CRP levels. Results: Postoperative complications occured in 28.5% (89/312) cases. Hemoglobin on postoperative day(POD) 3 (OR=0.977, 95% CI: 0.957 to 0.998, P=0.034), preoperative CRP (OR=1.209, 95% CI: 1.055 to 1.386, P=0.006) and CAR on POD 3 (OR=0.033, 95% CI: 0.016 to 0.067, P<0.01) were found to be significant independent relative factors for postoperative complications. The cutoff point of CAR on POD 3 was 0.325, patients with CAR≥0.325 were found to have more postoperative complications than those with CAR<0.325. The area under the curve of CAR on POD 3 and preoperative CRP were 0.872, 0.626, respectively. The positive predictive value of CAR on POD 3 was higher than that of preoperative CRP (79.9% vs. 55.1%). Conclusions: CAR is closely related to the occurrence of postoperative complications in colorectal surgery. Patients with CAR≥0.325 on POD 3 has higher incidence of postoperative complications.
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