Ligand-Free Palladium-Catalyzed Mizoroki-Heck Reaction to Synthesize Valuable α-Trifluoromethylacrylates
2020
Abstract α-Trifluoromethylacrylates were synthesized using efficient ligand-free palladium catalyzed Mizoroki-Heck reaction. With the alkyl trifluoromethylacrylates used as substrates, different catalytic systems were explored including Pd/C as a catalyst. Good to excellent yields were obtained with good chemical tolerance
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