DIAGNOSTIC BIOLOGIQUE DE L’HÉMOPHILIE

Introduction : It is a constitutional hemorrhagic disease of recessive transmission linked to X chromosome. Our objective work is to index the different cases in our service. Material and methods : During 18 months (april 2008 - september 2009), we account 124 haemophiliac cases diagnosed in our laboratory. Results : Our results interest a diagnosed 124 haemophiliac cases, including 99 cases of haemophilia A (79,83%) and 25 cases of haemophilia B (20,17%). 81 patients have an age less than 15 years old with a median of age as 13 years (limits 9 months - 39 years). The annual incidence of haemophilia is 82 cases. 62 persons had clinical symptomatology whereas the others were asymptomatic. These symptoms were arthropathy (59,67%), haemoarthrosis (27,41%), haematoma (4,83%), nosebleeds epistaxis, gingivorrhagia gums (4,83%) and ecchymosis (3,26%). According to the type of haemophilia: The severe forms of haemophilia (FVIII or FIX ≤ 1%) are 54,54% (54/99) for haemophilia A and 64% (16/25) for haemophilia B. Discussion: The diagnosis and classification of the haemophilia are possible in routine examination. Through the data of literature we propose a diagnostic strategy which makes it possible to consolidate the analysis of the constitutional haemostasis hemorrhagic diseases in particular of the haemophilia. Conclusion : The medical care of the haemophilia starts with the diagnostic stage. Our hope is to be able to extrapolate this study at the national level to set up a national file.