Amino acid transport and protein synthesis in ground squirrels during hibernation and artificial hypothermia

: The intensity of labelled leucine penetration from the blood-circulating system to the tissues and its incorporation into proteins of some organs of gophers have been studied under hibernation and hypothermia. It is shown that, in spite of the low temperature of the gopher body under hibernation, the intensity of amino acids transfer from the blood to the tissue was approximately the same as in active state. But the rate of proteins synthesis under hibernation considerably decreases though it is not completely stopped. Under artificial hypothermia of the mammals the transition of amino acids from the blood to the tissue is considerably hampered. Under these conditions the incorporation of labelled amino acids is completely stopped.