Reviews and model systems

Part I. Reviews of Checkpoint Controls, Their Involvement in the Development of Cancer, and Approaches to Their Investigation G1 and S-Phase Checkpoints, Chromosome Instability, and Cancer Hiroshi Nojima Analyzing the G2/M Checkpoint George R. Stark and William R. Taylor Analyzing the Spindle Checkpoint in Yeast and Frogs P. Todd Stukenberg and Daniel J. Burke Cell Cycle Checkpoint Control Mechanisms That Can Be Disrupted in Cancer Bipin C. Dash and Wafik El-Deiry Part II. Analyzing Checkpoint Controls in Diverse Model Systems Establishment of a Cell-Free System to Study the Activation of Chk2 Xingzhi Xu and David F. Stern Analyzing Checkpoint Controls in Human Skin Sandra Pavey and Brian G. Gabrielli Generation and Analysis of Brca1 Conditional Knockout Mice Chu-Xia Deng and Xiaoling Xu Analysis of Cell Cycle Progression and Genomic Integrity in Early Lethal Knockouts Eric J. Brown Xenopus Cell-Free Extracts to Study the DNA Damage Response Vincenzo Costanzo, Kirsten Robertson, and Jean Gautier A Xenopus Cell-Free System for Functional Analysis of the Chfr Ubiquitin Ligase Involved in Control of Mitotic Entry Dongmin Kang, Jim Wong, and Guowei Fang Control of Mitotic Entry After DNA Damage in Drosophila Burnley Jaklevic, Amanda Purdy, and Tin Tin Su Methods for Analyzing Checkpoint Responses in Caenorhabditis elegans Anton Gartner, Amy J. MacQueen, and Anne M. Villeneuve Assaying the Spindle Checkpoint in the Budding Yeast Saccharomyces cerevisiae Christopher M. Yellman and Daniel J. Burke Purification and Analysis of Checkpoint Protein Complexes From Saccharomyces cerevisiae Catherine M. Green and Noel F. Lowndes Index