New dehydrogenases, their derivatives and a process for preparing optically active alkanols

The present invention relates to proteins which have an enzymatic activity for the reduction of substituted alkanones such as 3-methylamino-1- (2-thienyl) -propan-1-one. The invention further relates to nucleic acids encoding these proteins, nucleic acid constructs, vectors, genetically modified microorganisms and to methods for preparation of optically active substituted alkanols such. B. (S) -3-methylamino-1- (2-thienyl) - (S) -propanol.