A new flavonoid from Sophora flavescens Ait.

AbstractA new flavonoid, 8-(3-hydroxymethyl-2-butenyl)-5,7,2′,4′-tetrahydroxyflavanone (1), along with seven known compounds, (2R)-3α,7,4′-Trihydroxy -5-methoxy-8-prenylflavanone (2), (2R)-3β,7,4′- Trihydroxy-5-methoxy-8-prenylflavanone (3), 3,7-dihydroxycoumarin (4), Shandougenines B (5), Specionin (6), Kushenol N (7) and Kushenol I (8) were isolated from the roots of Sophora flavescens. Among them, Compound 5 was isolated from Leguminous plants, and compounds 4 and 6 were isolated from Sophora flavescens for the first time. Their structures were elucidated by the aid of NMR, HRMS, HMBC and CD spectroscopic methods.