Studies on Polymorphisms of HNF-4α Gene and their Relarionships with Muscle Fiber and Growth Traits of Pigs

Hepatocyte nuclear factor-4α (HNF-4α) is a member of the hepatocyte nuclear factor family, which can be highly expressed in the liver. The family of genes regulating the differentiation of liver cells played a key role, while involved in liver glucose and lipid metabolism in the regulation of specific gene expression. HNF -4 α gene involved in regulating many aspects of life and metabolic activity in animals played an important role in growth and development. In this study, PCR-SSCP method to analyze the HNF -4 α gene single nucleotide polymorphisms associated with growth traits. The results showed that polymorphisms of SH1 BB genotype individuals for French Landrace effect of birth length was the highest. SH2 polymorphic loci on the legal systems of AB genotype in Landrace the effect of individual birth weight of the maximum value. At the same time, the site with a large public histological properties of porcine muscle fiber there were significant correlation. AB-type individual muscle fiber diameter and muscle fiber cross-sectional area were significantly lower than AA and BB type (P0.05).