Korelasi kadar laktat dengan Score for Neonatal Acute Physiology Perinatal Extension II (SNAPPE II) pada neonatus yang dirawat di NICU RSUP Sanglah, Bali, Indonesia
2019
Background: Infant mortality rate is one of the indicators of public
health degree that determines the human development index.
Various attempts were made to early detect the problems, one of
which was by assessing the severity of neonatal disease using Score
for Neonatal Acute Physiology Perinatal Extension-II (SNAPPE II)
which was associated with lactate levels as a metabolic response
and organ dysfunction due to critical illness that were suffered at
the Neonatal Intensive Care Unit (NICU).
Methods: A cross-sectional analytic study was conducted among
48 critically ill neonates treated at the Sanglah Hospital Denpasar
NICU. Samples were selected from affordable populations by
consecutive sampling. Data analysis was performed by Saphiro-
Wilk data normality test, correlation analysis using the Pearson
correlation coefficient, significant results if the value of p <0.05.
Latar Belakang: Angka kematian bayi menjadi salah satu
indikator derajat kesehatan masyarakat yang menentukan
indeks pembangunan manusia. Berbagai upaya dilakukan untuk
mendeteksi dini masalah yang dihadapi, salah satunya dengan
melakukan penilaian derajat keparahan penyakit neonatus
menggunakan Score for Neonatal Acute Physiology Perinatal
Extension-II (SNAPPE II) yang dihubungkan dengan kadar laktat
sebagai respon metabolisme dan disfungsi organ akibat sakit kritis
yang diderita neonatus di Neonatal Intensive Care Unit (NICU).
Metode: Penelitian analitik potong lintang dilakukan terhadap 48
neonatus sakit kritis yang dirawat di NICU RSUP Sanglah Denpasar.
Sampel dipilih dari populasi terjangkau dengan cara konsekutif
sampling. Analisis data dilakukan dengan uji normalitas data
Saphiro-Wilk, analisis korelasi menggunakan koefisien korelasi
Data were analyzed using SPSS version 17 for Windows.
Results: Most of the respondents were males (67%), the mean of
neonatal gestational age was 33 (± 3,2) weeks with the median
neonatal age at lactate sampling being 24 (24-48) hours. The
average age of the mother at delivery was 24 (21-40) years. The
mean lactate level in critically ill neonatal patients admitted to the
NICU was 3.2 (± 0,5) mmol / L. The mean SNAPPE II score on the
subject was 32 (20-42). There was a significant positive correlation
between the levels of lactate and the severity of the disease in
critically ill neonates in the NICU assessed by SNAPPE II (r = 0.45;
p = 0.004).
Conclusion: Lactate levels has a moderate positive correlation
with the severity of the disease in critically ill neonates in the NICU
assessed by SNAPPE II
- Correction
- Source
- Cite
- Save
- Machine Reading By IdeaReader
0
References
0
Citations
NaN
KQI