Clustering of AMPA recep - tors by the synaptic PDZ domain - containing protein PICK1

A process for purifying an aldehyde-containing ketone, which comprises catalytically hydrogenating a crude ketone containing minor amounts of aliphatic aldehydes at a temperature of from room temperature to about 100 DEG C. and a pressure of from atmospheric pressure to 10 kg/cm2xG, in the presence of hydrogen, a palladium-containing catalyst, and about 0.4 to about 15% by weight, based on the weight of the crude ketone, of an active hydrogen-containing compound having a higher boiling point than the ketone which is selected from the group consisting of water, aliphatic alcohols containing 3 to 7 carbon atoms, aliphatic carboxylic acids containing 1 to 6 carbon atoms, alicyclic alcohols containing 5 to 8 carbon atoms and alkylamines having an alkyl or cycloalkyl group containing 5 to 9 carbon atoms; distilling the hydrogenated product; and recovering a fraction containing the ketone.