Validated Spectroscopic Method for Estimation of Sumatriptan succinate in Pure and from Tablet Formulation

2009 
Sumatriptan succinate (sumatriptan) is a 5HT1D-Serotonin receptor agonist which is used to treat migraine and it has good vasoconstrictor properties. Only HPLC methods are available for analysis of the same but they are expensive. There is no UV method is available. Here we have developed a new, precise and simple UV spectrophotometric method for estimation of sumatriptan from tablet formulation. The drug obeyed the Beer's law and showed good correlation. It showed absorption maxima at 220 nm; double distlled water. The linearity was observed between 1 – 12 mcg/ml. The results of analysis were validated by recovery studies. The recovery was more than 99%. The method was found to be simple, accurate, precise, economical and robust.
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