Distinct mechanisms of dissemination of NDM-1 metallo Acinetobacter spp. in Argentina.

A four-year surveillance of carbapenem-resistant Acinetobacter spp. in Argentina identified 40 strains carrying bla NDM-1 Genome sequencing revealed that most were A. baumannii, while seven represented other Acinetobacter spp. The A. baumannii genomes were closely related, suggesting recent spread. bla NDM-1 was located in the chromosome of A. baumannii strains and on a plasmid in non-baumannii strains. A resistance gene island carrying bla PER-7 and other resistance determinants was found on a plasmid in some A. baumannii strains.