Abstract 21032: Ventricular Tachycardia and Atrial Fibrillation Complicating the Clinical Course of Tako-tsubo Cardiomyopathy: Results of the German Tako-tsubo Registry

Background: Arrhythmias may complicate the clinical course of tako-tsubo cardiomyopathy (TTC). This study evaluated the incidence and clinical relevance of ventricular arrhythmias and atrial fibrillation (AF) in pts of the German TTC registry. Methods: From 37 hospitals, 324 pts (296 f, 28 m, age 68±12) were included in the registry. Seven pts (2.2%) died (cardiogenic shock n=4; myocardial rupture, stroke and asystole n=1 each); 209 pts were continuously monitored and had daily ECG recordings for evaluation of arrhythmias. Results: Ventricular tachycardia (VT) was documented in 17 pts (8%) and newly diagnosed AF in 32 pts (15%). TTC pts with and without arrhythmias were compared. In pts with VT, time from symptom onset to hospital admission was shorter (3.8±3.2 vs 8.7±7.3 hours, p<0.001). Pulmonary edema (29% vs 12%, p<0.05), need for intraaortic balloon pumping (6% vs 0.5%, p<0.05), resuscitation (18% vs 3%, p<0.002) and left ventricular thrombi (12% vs 3%, p=0.05) were seen more frequently. The QTc inte...