T1086 Stress Ulcer Prophylaxis out of Intensive Care Setting: Prospective Evaluation of a Common Practice

normal (8 pts), showed scalloping/atrophy (4 pts), congestion/edema (1 pt), mild nodularity (1 pt) and was unknown for 4 patients. Associations with other gastrointestinal diseases included collagenous gastritis (1 pt), lymphocytic gastritis (2 pts), collagenous colitis (1 pt), chronic gastritis (4 pts), reactive gastropathy (1 pt), erosive gastritis (1 pt) and high grade T cell lymphoma of esophagus (1 pt). Three patients had a personal history of celiac sprue. No duodenal pathology follow-up was available in 14 of 18 cases. Of the four cases with duodenal biopsy follow-up, one case of CS persisted at 9 months although duodenal biopsy at 20 months was normal. One patient's biopsy was normal after 10 months. One patient showed peptic duodenopathy at 12 months, but no evidence of celiac or CS. One patient showed evidence of celiac sprue at 22 months, but had no increase of subepithelial collagen. Conclusion: This nationwide study indicates that CS has a female predominance, random geographical distribution and usually occurs above the age of 50. Clinical symptoms are varied and the endoscopic appearance is often normal or shows atrophy or scalloping. Limited follow-up data suggests that histologic features of CS are reversible.