Sumoylated hnRNPA2B1 controls the sorting of miRNAs into exosomes through binding to specific motifs

Cells secrete micro-RNAs by packaging them into exosomes; however, the mechanisms by which this packaging occurs are unclear. Here, the authors identify a sequence motif that confers exosomal targeting to micro-RNAs and identify a ribonucleoprotein complex that plays a role in this process.