Serum Amino-Terminal Pro-B Type Natriuretic Peptide (NT-pro BNP) Status among Heart Failure (HF) Patients in Bangladesh.

This cross sectional study was carried out in the Department of Biochemistry, Mymensingh Medical College in collaboration with the Department of Cardiology, Mymensingh Medical College Hospital, Mymensingh, Bangladesh from January 2018 to December 2018. The aim of the study was to explore the relationship of serum NT-pro BNP in heart failure (HF) patients as a means to monitor the possibility of management of these patients. A total of 120 subjects were included in this study. Among them 60 were diagnosed HF patients denoted as case group and 60 were normal healthy individuals denoted as control group. Serum NT-pro BNP concentration was measured by Fluorescence Immunoassay (FIA) from each sample. Statistical analysis was performed by SPSS windows package, version 21. Among the study group the mean serum NT-pro BNP levels were 4931.93+/-7229.36 and 999.47+/-49.99 pg/ml in case and control group respectively. Analysis showed that the mean serum NT-pro BNP level was highly significant (p<0.001) increased in heart failure patients comparison to that of control group.