Multiple primary triple cancer of the thyroid breast and lung and 21-gene expression detection: A case report

Objective: To discuss the clinical and pathological features and the diagnosis and therapy of multiple primary triple cancers of thyroid, breast and lung. Methods: The medical records of a case of multiple primary triple cancers of thyroid, breast and lung were reviewed retrospectively, and the clinicopathological features as well as the diagnosis and therapy were analyzed. Results: Multiple primary triple cancers of this case were performed with surgical operation. Because this case had lymph node-negative and estrogen receptor-positive early-stage breast cancer, the 21-gene detection was performed, and the recurrence score showed low risk, so the case didn’t need chemotherapy treatment.  Conclusion: The principle of treatment and the prognosis of multiple primary cancers are similar to those of single cancer, and the treatment options for patients with early-stage breast cancer with estrogen receptor-positive and lymph node-negative may refer to the 21-gene recurrence score system. DOI:10.3781/j.issn.1000-7431.2017.24.760