RBM5-AS1 Is Critical for Self-Renewal of Colon Cancer Stem-like Cells

Serena Di Cecilia,Fan Zhang,Ana Sancho,SiDe Li,Francesca Aguilo,Yifei Sun,Madhumitha Rengasamy,Weijia Zhang,Luigi Del Vecchio,F. Salvatore,Martin J. Walsh

RBM5-AS1 Is Critical for Self-Renewal of Colon Cancer Stem-like Cells

2016

Serena Di Cecilia
Fan Zhang
Ana Sancho
SiDe Li
Francesca Aguilo
Yifei Sun
Madhumitha Rengasamy
Weijia Zhang
Luigi Del Vecchio
F. Salvatore
Martin J. Walsh

Cancer-initiating cells (CIC) undergo asymmetric growth patterns that increase phenotypic diversity and drive selection for chemotherapeutic resistance and tumor relapse. WNT signaling is a hallmar ...

Keywords:

Wnt signaling pathway
Immunology
Colorectal cancer
Phenotype
Biology
Cell and molecular biology
Asymmetric growth
Transcription factor
Immediate early protein
Basic helix-loop-helix leucine zipper transcription factors
Beta-catenin
Cyclin D1

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