Process for producing high-standard prednisolone sodium phosphate

The invention discloses a process for producing high-standard prednisolone sodium phosphate, and belongs to the field of chemistry. The process adopts prednisolone phosphate as a raw material, and comprises the following steps: A, adding prednisolone phosphate into pure water, stirring and adjusting the temperature to 20-40 DEG C, wherein the pure water volume (unit: milliliter) is 5-10 times of that of prednisolone phosphate (unit: g); B, dropwise adding a sodium hydroxide solution in the state of monitoring the pH value, and stirring the reaction system during adding until the system pH is 9.5, wherein the temperature of the system is controlled to be 25-35 DEG C during adding; C, filtering the reactant when the pH value becomes constant, and drying the filtrate after filtration to obtain high-standard prednisolone sodium phosphate. The process provided by the invention is simple and easy to implement, and is suitable for being applied to the production of high-standard prednisolone sodium phosphate.