Chemical constituents of Euphorbia peplus

Abstract Phytochemical investigation of the whole plant of Euphorbia peplus Linn. led to the isolation of previously uncharacterized jatrophane type diterpenoid euphopepluanone L (1), along with seven known compounds, including three diterpenes (2–4), three bisnorsesquiterpenes (5–7), and a monoterpene (8). Their chemical structures were established based on extensive spectroscopic analysis. Compounds 3 (20-deoxyingenol) and 5–8 were firstly isolated from E. peplus, while PBI 345 (5) reported from the genus for the first time. Furthermore, the chemotaxonomic significance of the isolates was discussed.