Synthesis and structure of certain O-pyrimidinyl-oximes of 2,2-dimethyltetrahydro-4-pyranone

By reactions of substituted chloropyrimidines with the sodium salt of 2,2-dimethyltetrahydro-4-pyranone oxime, pyrimidinyloximes of 2,2-dimethyltetrahydro-4-pyranone have been obtained. On the basis of x-ray diffraction studies of the O-(2,4-dimethyl-6-pyrimidinyl)oxime of 2,2-dimethyltetrahydro-4-pyranone, it has been shown that the oxygen atoms of the oxime group and the carbon in position 2 of the pyran ring are in theanti position relative to the double bond of the oxime.