Effects of Sarcandra glabra extract on immune activity in restraint stress mice

Objective:To study the protective effect of Sarcandra glabra extract(SGE) on immune system in restrained mice. Method:The male C57BL/6 mice were randomly divided into normal control group,stress control group,125,500 mg·kg-1 SGE group. The spleen lymphocyte suspensions of each group were prepared. The parameters of spleen T cells subsets,NK cell and NKT cell proportion and number was detected by Flow cytometry. Result:SGE regulated the balance of T cell subsets,increased the percent of NK cells and NKT cell proportion and number in restrained mice. Conclusion:SGE has immunologic protective effect in restrained mice probably via the amelioration of immune cells proportion and number.