A case of Plasmodium malariae infection identified by metgenomic next-generation sequencing and literature review

2019 
疟疾是旅行归来者发热最常见的原因,因检测手段的局限,常被误诊和漏诊。本文报道1例35岁中国男子从尼日利亚回国后发烧10 d,外周血疟原虫涂片3次及血培养3套均为阴性,同步进行的血宏基因二代基因检测技术(mNGS)提示三日疟,治疗后迅速好转,后经PCR确诊。本例病例报告提示mNGS可帮助临床医师快速精准识别疟疾感染。
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