Revealing some virus infections by lymphocyte laser scattering
2010
Light scattering patterns have been calculated for a simple optical model constructed for single smooth and nonsmooth
lymphocytes of healthy and infected individuals. It has been shown that the smooth and nonsmooth cells can be resolved
using the intensities of the sideward and backward scattered light. We have found by calculations and validated by the
flow-cytometer experiments that intensity distributions for the cells of lymphocyte populations can be used as a
preliminary signatures of some virus infections. Potential biomedical applications of the findings for label-free flowcytometry
detecting of individuals infected with viruses of hepatitises B or C and some others viruses are presented.
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