Epidermal growth factor receptor polymorphisms and risk for toxicity in paediatric patients treated with gefitinib

Trevor McKibbin,Wei Zhao,Michael Tagen,Najat C. Daw,Wayne L. Furman,Lisa M. McGregor,J. Russell Geyer,Jeffrey W. Allen,Clinton F. Stewart

Epidermal growth factor receptor polymorphisms and risk for toxicity in paediatric patients treated with gefitinib

2010

Trevor McKibbin
Wei Zhao
Michael Tagen
Najat C. Daw
Wayne L. Furman
Lisa M. McGregor
J. Russell Geyer
Jeffrey W. Allen
Clinton F. Stewart

Purpose To investigate associations between germline genetic variations in the epidermal growth factor receptor (EGFR) and toxicity in paediatric patients treated with gefitinib.

Keywords:

Pharmacogenomics
Cancer
Gefitinib
Epidermal growth factor receptor
Immunology
Risk factor
Tyrosine-kinase inhibitor
Cancer research
Germline mutation
Medicine
Growth factor receptor
Toxicity

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