Juvenile myelomonocytic leukemia
2015
Juvenile myelomonocytic leukemia (JMML) is a rare pediatric malignancy, which presents in infancy or early childhood with myeloproliferative features and hepatosplenomegaly. JMML is Philadelphia chromosome negative with aggressive clinical course. We repor t a case of JMML in a three year old female child with recurrent fever, anemia and hepatosplenomegaly. Her blood examination showed leucocytosis, monocytosis and elevated HbF without increase in blasts. Philadelphia chromosome was negative. The disease pro thrombocytopenia and patient expired due to intracranial bleed within two months of diagnosis.
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