Acute Skin Necrosis with Compartment Syndrome in the Upper Extremity

We present the case of a 43-year-old female patient who developed acute blistering and necrosis of the skin of the left upper limb following a routine cannulation. The case highlights the importance of early recognition of compartment syndrome in the non-trauma setting and also introduces the angiosome concept to explain why extensive degloving inevitably results in skin necrosis.