Adhesion of Methicillin-Resistant Staphylococcus aureus and Candida albicans to Parylene-C–Coated Polymethyl Methacrylate

PURPOSE: To determine whether coating polymethyl methacrylate (PMMA) discs with Parylene-C would reduce Staphylococcus aureus and Candida albicans biofilm formation. MATERIALS AND METHODS: MRSA and Candida albicans single and dual biofilms were grown for 48 hours in artificial saliva on parylene-C-coated or uncoated PMMA, and the viable biofilm colony-forming units were counted. RESULTS: There was no significant difference in the count of viable methicillin-resistant Staphylococcus aureus or Candida albicans recovered from single- or dual-species biofilms between coated and uncoated PMMA discs. CONCLUSION: Parylene-C does not prevent biofilm formation on PMMA.