Radix Paeoniae Rubra stimulates osteoclast differentiation by activation of the NF-ΚB and mitogen-activated protein kinase pathways

Background Radix Paeoniae Rubra (RPR), a traditional Chinese herb, has anti-inflammatory and immuno-regulatory properties. This study explored the effects of RPR on stimulation of osteoclast differentiation in RAW264.7 cells and peripheral blood mononuclear cells (PBMC)s.