Optimal induction of myeloma cell death requires dual blockade of phosphoinositide 3-kinase and mTOR signalling and is determined by translocation subtype

Chloe Stengel,Ching Wai Cheung,John Quinn,Kwee Yong,Asim Khwaja

Optimal induction of myeloma cell death requires dual blockade of phosphoinositide 3-kinase and mTOR signalling and is determined by translocation subtype

2012

Chloe Stengel
Ching Wai Cheung
John Quinn
Kwee Yong
Asim Khwaja

Optimal induction of myeloma cell death requires dual blockade of phosphoinositide 3-kinase and mTOR signalling and is determined by translocation subtype

Keywords:

Cancer research
RPTOR
Programmed cell death
PI3K/AKT/mTOR pathway
Phosphoinositide 3-kinase
Cell biology
Blockade
Signal transduction
Chromosomal translocation
Biology
Multiple myeloma
Protein kinase B
MAPK/ERK pathway
Cell growth
Cytotoxic T cell

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