Modular Neck vs Nonmodular Femoral Stems in Total Hip Arthroplasty—Clinical Outcome, Metal Ion Levels, and Radiologic Findings

Abstract Background Modular neck femoral stem (MNFS) for total hip arthroplasty (THA) was introduced to optimize the outcome, but created concerns about pain, elevated blood metal ion levels, and adverse reaction to metal debris such as pseudotumors (PTs), related to corrosion between femoral neck and stem. We compared these outcomes in patients with MNFS or nonmodular femoral stem (NFS) THA. Methods Thirty-three patients with unilateral MNFS THA were compared with 30 patients with unilateral NFS THA. Levels of pain, serum cobalt, serum chromium were determined. Magnetic resonance imaging was performed to describe PT and fatty atrophy of muscles. Results The MNFS and NFS group had a mean follow-up of 2.3 and 3.1 years, respectively. Four and 13 patients in the MNFS and NFS group had pain, respectively ( P  = .005). The MNFS group had higher levels of serum cobalt ( P P  = .006). PTs were present in both the MNFS (n = 15) and NFS (n = 7) groups ( P  = .066). PTs were related to serum cobalt ( P  = .04) but not to pain or serum chromium. Fatty atrophy prevalence in the piriformis and gluteal muscles were higher in patients with MNFS ( P  = .009 and P  = .032, respectively). Conclusion More patients in the NFS group had pain. Serum cobalt and chromium levels were higher in the MNFS group. Prevalence of PTs was twice as high in the MNFS group, but the difference was insignificant.