How to prepare optically active alcohols from alkanones with dehydrogenase azoarcus

The present invention provides a compound of formula (I) wherein, n is an integer from 0 to 5; Cyc is optionally saturated or unsaturated optionally substituted mononuclear or polynuclear carbocyclic or heterocyclic represents an expression of ring, and R In the present invention, the formula (II) wherein, n, Cyc, and R Enzymatically reducing the compound of formula (II) to the compound of formula (I), it is consumed during the reaction by sacrificing ketones corresponding reacted sacrificial alcohol using an enzyme (E) the reduction equivalents regenerated was removed from the reaction medium at least partially sacrificial ketone, then isolated so generated product (I).