Genomic analysis of myeloproliferative neoplasms in chronic and acute phases

Myeloproliferative neoplasms (MPNs) are chronic, clonal hematopoietic disorders that include polycythemia vera (PV), essential thrombocytosis (ET), and primary myelofibrosis (PMF). A substantial proportion transforms into acute myeloid leukemia (AML) with a dismal prognosis.[1][1] Mutually-exclusive