On Anaesthetica by Johann N. von Nussbaum who Introduced the Concept of Local Anesthesia to Japan

: Because the Japanese word of Masui (Anesthesia) was originally coined to mean general anesthesia in 1850, there was no Japanese phrase corresponding to general anesthesia in the period between 1850 and 1877. In 1878, Tadanori Ishiguro, a military surgeon who was impressed by Johann N. von Nussbaum's Andsthetica, published Shitu narabini Masuiho (Analge- sia and Anesthesia). In this book, he coined new Japa- nese phrases Kyokusho Masui and Zenshin Masui which corresponded to German phrases Lokale Anaes- thesie and Allgemneine Anaesthesie, and he described the definition of those terms. Since then, the terms, local anesthesia and general anesthesia, have prevailed in Japan.