Clinical Drug-Drug Interaction Data: Effects of Co-administered Drugs on Pharmacokinetics of Antiretroviral Agents

This chapter summarizes the clinical drug-drug interaction data for each antiretroviral agent. The effects of co-administered drugs on the pharmacokinetics of the following agents will be presented: Nonnucleoside reverse transcriptase inhibitors (NNRTIs): delavirdine, efavirenz, etravirine, nevirapine, and rilpivirine Nucleoside reverse-transcriptase inhibitors (NRTIs): abacavir, didanosine, and zidovudine Protease inhibitors (PIs): atazanavir, darunavir, fosamprenavir, emtricitabine, lamivudine, stavudine, tenofovir, indinavir, nelfinavir, ritonavir, saquinavir, tipranavir, and lopinavir Fusion Inhibitors: enfuvirtide Entry inhibitors: maraviroc Integrase inhibitors: dolutegravir, elvitegravir, raltegravir