Multicomponent access to novel dihydroimidazo[1′,5′:1,2]pyrido[3,4-b]indol-2-ium salts and indoles by means of Ugi/Bischler–Napieralski/heterocyclization two step strategy
2014
Abstract A simple, efficient and general two step procedure, through a sequential Ugi reaction followed by a Bischler–Napieralski/heterocyclization tandem closure, to give novel 6,11-dihydro-5 H -imidazo[1′,5′:1,2]pyrido[3,4- b ]indol-2-ium salt derivatives, is described. By changing the amine and the acid components with ammonium formate, the same procedure affords 6,11-dihydro-5 H -imidazo[1′,5′:1,2]pyrido[3,4- b ]indole derivatives.
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