Discussion of Pathogen and Potential Therapeutic Strategy for Triple Negative Breast Cancer Based on a Rare Case Study

Triple Negative Breast Cancer (TNBC) accounts for 10-22% of all breast cancer patients. Here we report a rare case of TNBC patient with metastasis to opposite chest organs, left abdomen is rectus muscle, eventually to brain. According to course of disease and gene expression profile in this case, we discuss the pathogen and potential therapeutic strategy for TNBC: DNA mythelation may be the main cause for the negative expression and mutations of breast cancer biomarkers. Hormone therapy is dangerous for TNBC patients. Immunomodulators and antineovascularization may bring the breakthrough for increasing survival rate of TMBC patients.