Nervous system changes in patients treated with penicillin during the period of symptomatic and early asymptomatic syphilis

: The results of cerebrospinal fluid examination of 451 patients treated for syphilis were analysed. In 34 patients abnormalities were found in the protein level, cell number and serological investigations. Thus, there is an absolute indication to cerebrospinal fluid examination in each case in which serological tests remain positive despite adequate specific therapy.