Optimization, and in vitro and in vivo evaluation of etomidate intravenous lipid emulsion.

Dandan Geng,Li Yan,Wang Chunyan,Ren Bo,Heping Wang,Chensi Wu,Yirong Zhang,Zhao Linlin,Zhao Ligang

Optimization, and in vitro and in vivo evaluation of etomidate intravenous lipid emulsion.

2021

Dandan Geng
Li Yan
Wang Chunyan
Ren Bo
Heping Wang
Chensi Wu
Yirong Zhang
Zhao Linlin
Zhao Ligang

The aim of this investigation was to develop an etomidate intravenous lipid emulsion (ETM-ILE) and evaluate its properties in vitro and in vivo. Etomidate (ETM) is a hydrophobic drug, and organic s...

Keywords:

Intravenous lipid emulsion
Pharmacology
In vivo
hydrophobic drug
Etomidate
tissue distribution
In vitro
Chemistry
Pharmacokinetics

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