Phytomolecules of Terminalia macroptera stem bark extracts Guill et Perr (Combretaceae) and antibacterial activity

Today, the phenomenon of multidrug resistance is growing and makes inefficient use of many antibiotics on the market. Faced with this therapeutic impasse, the Scientific World will invest the field of plants, in search of new molecules. It is in this context that the study on Terminalia maccroptera was initiated.The main objective of this study is to characterize the different phytomolecules of the 70% ethanolic extract of Terminalia macroptera by GC-MS and to identify the molecules susceptible to antibacterial activity.Tri phytochemistry was performed using the tube reagent method for determining chemical components and gas chromatography-mass spectrometry (GC-MS) to characterize the existing phytomolecules in the extract.The tri-phytochemical study showed the chemical groups: Poly-phenols, Flavonoids, saponins, tannins gallic, Cardiac glycosides, sterols and terpenes. The GC-MS has firstly confirmed the great chemical groups, and also identified 20 molecules accompanied by their mass spectra, their molecular weight and their chemical structures.Among these molecules Beta-sitosterol is the most important in ethanol extract70%. It belongs to the family of triterpenes (known for their antibacterial activity). This molecule is therefore responsible for the antibacterial activity of our extract.