Abstract 14549: Impact of Ventricular Fibrillation on In-Hospital Mortality and Long-Term Mortality After Myocardial Infarction: The FAST-MI Registry

Little data exists in the contemporary era on the impact of ventricular fibrillation (VF) at the acute stage of AMI on early and long-term outcomes. We analysed the impact of in-hospital VF on in-hospital mortality and 3-year survival in hospital survivors of the FAST-MI registry, which included patients hospitalized within 48 hours of onset of AMI in France in 2005. Overall, 3670 patients were included, of whom 75 (2.0%) developed VF. Patients with VF were younger (63±15 vs 67±14 years, p<0.001), had a higher GRACE risk score (166 ±45 vs 149±37, p<0.001), and had more frequently STEMI (73% vs 50%, p<0.001). They were more frequently current smokers (45% vs 29%, p=0.002). In-hospital death was 25% in patients with, vs 5% in those without VF (p<0.001). In logistic regression analyses including baseline characteristics and management variables, VF was independently associated with a major risk of in-hospital death (OR 6.16 [3.09-12.26]). In the 3463 hospital survivors, however, 3-year survival was 91% in pa...