The in vitro influence of Rhodiola quadrifida extracts on non-specific cellular immunity in pigs

Roots and rhizomes of herbs belonging to the genus Rhodiola (Crassulaceae) are traditionally used in Asia as a tonic, adaptogen, anti-microbial and anti-inflammatory drugs. The aim of this work was to study the in vitro immunomodulatory activity of aquaeous and hydro-alcoholic extracts of underground parts of Rhodiola quadrifida in blood leukocyte cultures of pigs. Both extracts in concentration up to 10 μg/ml stimulated granulocyte potential killing (PKA) and respiratory burst (RBA) activity. In higher concentrations the suppression of these reactions were seen.