MicroRNA-32 Upregulation by 1,25-Dihydroxyvitamin D3 in Human Myeloid Leukemia Cells Leads to Bim Targeting and Inhibition of AraC-Induced Apoptosis

Treatment of acute myeloid leukemias that remain poorly managed in the clinic may benefit from agents that can block the expression of a microRNA that limits expression of the proapoptotic protein Bim.